1White Snakeroot
Nahhan / Getty ImagesWhite Snakeroot is a perennial plant that gets up to five-feet tall and has small white flowers that grow in clusters. It contains a toxin by the name of tremetone, which is highly poisonous and can be fatal for both humans and animals. It was famously responsible for the death of Abraham Lincoln's mother, who drank milk from a cow that had eaten a White Snakeroot.
2Hyacinth
EBlokhina / Getty ImagesThere's so much to love about hyacinths, from their bright colors to their delightful scent. While beautiful, the flowers contain calcium oxalate crystals and narcissus-like alkaloids, making them poisonous to both humans and animals like cats and dogs. They can cause everything from skin irritation to severe digestive issues.
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3Poison Ivy
Denise Panyik-Dale / Getty ImagesAs its name suggests, poison ivy is a poisonous plant. It contains a sap called urushiol that irritates the skin upon contact, causing blisters and an itchy rash. Poison ivy is easily recognizable, thanks to its three-leaf clusters—that you definitely want to stay away from. One thing to note is that the plant doesn't stop being poisonous in the winter or when it's dead, as the sap can remain active even years after the plant has been cut down.
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4Poinsettia
PDerrett / Getty ImagesPoinsettias may be a holiday decor staple, but they are also poisonous. While their toxicity level is mild, extra care and caution is required, especially if you have pets in the home. Poinsettias contain a milky white sap and if pets or children ingest that or the leaves, it can lead to skin and mouth irritation as well as intense digestive issues.
5Clematis
Justus de Cuveland / Getty ImagesBoth the flowers and leaves on a Clematis plant are poisonous to humans and animals. They contain a toxic agent called protoanemonin that can lead to mouth ulcers, irritation, and digestive issues when the plant is consumed. Additionally, touching the plant can cause skin irritation, so make sure you're wearing gloves whenever you prune or plant Clematis.
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6Larkspur
Andrea Astes / Getty ImagesLarkspur, also known as Delphinium, contains diterpene alkaloids which make every part of the plant poisonous—especially the seeds and any new growth. While it's poisonous to humans as well as animals, cattle are among the most vulnerable to its toxic agents. If they graze on Larkspur, it can lead to respiratory paralysis and death.
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7Morning Glory
kinpouge05 / Getty ImagesYou can instantly recognize a Morning Glory's trumpet-shaped blooms. While the popular vining plant has flowers that aren't toxic, the seeds are. In fact, the seeds contain chemical compounds that make them similar to LSD. They are toxic for humans and pets, and eating them can cause hallucinations, dizziness, numbness, and digestive issues.
8Monkshood
Tom Meaker / Getty ImagesAconitum is a toxic perennial plant also referred to as Monkshood, because the vibrant flower petals' droopy shape looks like a monk's hood. It blooms in mid-summer and is known to be one of the most poisonous plants because of the high content of toxic alkaloids, which are mainly located in the roots and tubers. Even a tiny ingested amount can cause death due to heart failure.
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9Amaryllis
Marketa Bement / Getty ImagesTypically purchased during the holidays, Amaryllis is a festive plant that happens to be poisonous. Keep the plant away from children and pets, as it contains licoryne and other toxic alkaloids that can lead to vomiting, diarrhea, and abdominal pain. While the whole plant is poisonous, the bulb has the highest concentration of toxins.
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10Virginia Creeper
Boris Zhitkov / Getty ImagesAlthough not quite as poisonous as Poison Ivy, Virginia Creeper can still be harmful. It can cause skin irritation, blisters, and a rash when touched, and lead to digestive issues and abdominal pain when ingested. In addition to the leaves being poisonous, the berries are also toxic as they (and the sap) contain oxalate crystals.
11Death Camas
Murphy_Shewchuk//Getty ImagesThis pretty perennial is found throughout the western U.S., but don't let its beauty fool you—every part of this plant is highly toxic to both humans and animals. If it's ingested, it can lead to symptoms like vomiting, stomach pain, tremors, and weakness.
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12Cotoneaster
Artist and photographer from Poland//Getty ImagesWhile birds typically gravitate towards Cotoneaster's vibrant berries, this plant can be extremely poisonous to humans and animals (cats and dogs included!). It's native to Europe and certain parts of Asia.
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13Iris
Pauline Lewis//Getty ImagesThese common garden plants are known to be harmful to humans and pets. Keep in mind that coming in contact with its roots and leaves can irritate the skin, so it's best to wear long sleeves and gloves if you're going to be handling them.
14Lupine
Westend61//Getty ImagesThis perennial, which is a member of the pea family and can be found across the U.S., might boast visual appeal, but it contains alkaloid chemicals, which can cause harm to humans and animals. If ingested, parts of the lupine can cause upset stomach, difficulty breathing, and even seizures.
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15Night Blooming Jasmine
Karyn R. Millet//Getty ImagesThis invasive species can be extremely harmful to pets and animals if it's ingested. Symptoms can range from vomiting to seizures if one is exposed to its toxins.
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16Wild Parsnip
tirc83//Getty ImagesAt some point, you might have spotted this toxic plant by a roadside or in an open field. It should be left alone, as its sap can cause severe rashes, blisters, and skin discoloration.
17Angel's Trumpet
Luis Diaz Devesa//Getty ImagesThis warm-weather plant is a go-to for adding beauty to gardens, but beware since it's part of the nightshade family. The entire plant—from the seeds to the flowers–is toxic and harmful to humans and animals.
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18Autumn Crocus
Wolfgang Kaehler//Getty ImagesThis spring perennial, which is also known as meadow saffron and naked lady, may be easy to care for, but every part of the plant is highly toxic to humans and pets. Poisoning symptoms range from diarrhea to burning in the mouth.
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19Jimson Weed
DeepDesertPhoto//Getty ImagesWith green leaves—that are sometimes tinged with purple—jimson weed is incredibly unsafe when ingested or inhaled. Although used to treat asthma and other health conditions, it can lead to nausea, vomiting, and hallucinations.
20Lantana (Lantana camara)
AYImages/ GettyKeep these colorful plants away from your children. Although toddlers and babies may find them attractive, they're toxic and poisonous (even to dogs and cats).

Overseeing all things home for GoodHousekeeping.com and HouseBeautiful.com, Lauren swoons over midcentury design and employs tough-love approach to decluttering (just throw it away, ladies). She loves anything neon coral, puts bacon on her veggie burgers, and would follow Tina Fey and Amy Poehler to the end of the earth.

Maria Sabella is a lifestyle writer with a passion for home and interiors — from paint colors and holiday decor to the latest design trends. Her work has appeared in outlets including Better Homes & Gardens, The Spruce, BuzzFeed and Bustle.
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